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Olivier Cuvillier Selected Research

sphingosine kinase

1/2022Sphingosine Kinase-1 Is Overexpressed and Correlates with Hypoxia in Osteosarcoma: Relationship with Clinicopathological Parameters.
8/2019Sphingosine kinase-1 predicts overall survival outcomes in non-small cell lung cancer patients treated with carboplatin and navelbine.
1/2018Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain.
3/2017Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression.
10/2016FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model.
5/2015Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer.
1/2014Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.
12/2010Sphingosine kinase-1 activity and expression in human prostate cancer resection specimens.
11/2010FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1.
10/2010The sphingosine kinase-1 survival pathway is a molecular target for the tumor-suppressive tea and wine polyphenols in prostate cancer.
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Olivier Cuvillier Research Topics

Disease

26Neoplasms (Cancer)
01/2022 - 05/2003
13Prostatic Neoplasms (Prostate Cancer)
10/2020 - 12/2005
10Hypoxia (Hypoxemia)
01/2022 - 10/2008
7Neoplasm Metastasis (Metastasis)
10/2020 - 05/2009
4Alzheimer Disease (Alzheimer's Disease)
01/2018 - 04/2012
4Adenocarcinoma
09/2012 - 01/2003
2Multiple Sclerosis
03/2020 - 11/2010
2Inflammation (Inflammations)
01/2014 - 01/2012
2Pancreatic Neoplasms (Pancreatic Cancer)
04/2009 - 01/2003
1Osteosarcoma (Osteogenic Sarcoma)
01/2022
1Carcinogenesis
10/2020
1Starvation
10/2020
1Obesity
01/2020
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2019
1Amyloid Plaque
01/2018
1Vascular Remodeling
10/2016
1Renal Cell Carcinoma (Grawitz Tumor)
10/2016
1Niemann-Pick Diseases (Niemann Pick Disease)
01/2011
1Urogenital Neoplasms
12/2010
1Neuroblastoma
08/2007
1Ischemia
01/2007
1Infarction (Infarctions)
01/2007
1Melanoma (Melanoma, Malignant)
06/2003
1Necrosis
12/2002
1Breast Neoplasms (Breast Cancer)
11/2002
1Hepatocellular Carcinoma (Hepatoma)
01/2002

Drug/Important Bio-Agent (IBA)

21sphingosine kinaseIBA
01/2022 - 12/2005
18sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2022 - 12/2005
10SphingolipidsIBA
01/2020 - 12/2002
9CeramidesIBA
09/2012 - 06/2003
6Transcription Factors (Transcription Factor)IBA
01/2020 - 10/2008
6LipidsIBA
08/2019 - 10/2008
5SphingosineIBA
01/2014 - 05/2003
4Proteins (Proteins, Gene)FDA Link
10/2020 - 04/2009
4Oxygen (Dioxygen)IBA
02/2017 - 05/2009
3Fingolimod Hydrochloride (FTY720)FDA Link
01/2022 - 11/2010
3LyasesIBA
08/2019 - 09/2012
3Peptides (Polypeptides)IBA
01/2018 - 08/2007
3Docetaxel (Taxotere)FDA Link
09/2012 - 12/2005
3EnzymesIBA
09/2012 - 05/2003
3Hormones (Hormone)IBA
11/2010 - 11/2009
2Sphingosine-1-Phosphate ReceptorsIBA
01/2022 - 11/2010
2Amyloid (Amyloid Fibrils)IBA
01/2018 - 04/2012
2GoldIBA
01/2018 - 10/2014
2GemcitabineFDA Link
10/2016 - 04/2009
2LigandsIBA
10/2014 - 01/2003
2Biological ProductsIBA
01/2014 - 01/2012
2Amyloid beta-PeptidesIBA
01/2014 - 08/2007
2Pharmaceutical PreparationsIBA
11/2010 - 04/2009
2Messenger RNA (mRNA)IBA
06/2010 - 02/2007
2Phosphotransferases (Kinase)IBA
11/2009 - 10/2008
2CamptothecinIBA
07/2008 - 12/2005
2CaspasesIBA
11/2002 - 01/2002
1Phospholipase DIBA
10/2020
11-dodecylpyridoxal (PLD)IBA
10/2020
1Protein Isoforms (Isoforms)IBA
10/2020
1AntioxidantsIBA
01/2020
1Vinorelbine (Navelbine)FDA LinkGeneric
08/2019
1Carboplatin (JM8)FDA LinkGeneric
08/2019
1Cisplatin (Platino)FDA LinkGeneric
01/2018
1tau Proteins (tau Protein)IBA
01/2018
1Monoclonal AntibodiesIBA
05/2015
1Hypoglycemic Agents (Hypoglycemics)IBA
02/2015
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
02/2015
1Metformin (Glucophage)FDA LinkGeneric
02/2015
1GTP Phosphohydrolases (GTPases)IBA
02/2015
1carbeneIBA
10/2014
1Biomarkers (Surrogate Marker)IBA
05/2014
1Phosphates (Orthophosphate)IBA
01/2012
1Indicators and Reagents (Reagents)IBA
11/2011
1neodymium pyrocatechin disulfonate (NPD)IBA
01/2011
1Complement System Proteins (Complement)IBA
12/2010
1TeaIBA
10/2010
1PolyphenolsIBA
10/2010
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
10/2010
1ResveratrolIBA
10/2010
1vineatrolIBA
10/2010
1polyphenon EIBA
10/2010
1AndrogensIBA
11/2009
1Small Interfering RNA (siRNA)IBA
04/2009
1ElementsIBA
07/2008
1B 5354cIBA
07/2008
1Monoamine Oxidase (MAO)IBA
01/2007
1Taxoids (Taxanes)IBA
12/2005
1ceramide glucosyltransferaseIBA
06/2003
1miglustat (Zavesca)FDA Link
06/2003
1Somatostatin Receptors (Somatostatin Receptor)IBA
01/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2002
1AntibodiesIBA
11/2002
1Acetaminophen (Paracetamol)FDA LinkGeneric
01/2002

Therapy/Procedure

8Therapeutics
10/2020 - 08/2008
7Drug Therapy (Chemotherapy)
01/2022 - 12/2005
4Radiotherapy
10/2020 - 11/2010
1Prostatectomy (Retropubic Prostatectomy)
09/2012